(c) Copyright 2009, Biotech Week via NewsRx.com
2009 JUL 22 - (NewsRx.com) -- Investigators publish new data in the report 'Chemically assisted microbial production of succinic acid by the yeast Yarrowia lipolytica grown on ethanol.' According to a study from Russia, "A new two-step process of production of succinic acid (SA) has been developed, which includes the microbial synthesis of alpha-ketoglutaric acid by the yeast Yarrowia lipolytica (step 1) and subsequent oxidation of the acid by hydrogen peroxide to SA (step 2). The maximum concentration of SA and its yield were found to be 63.4 g l(-1) and 58% of the ethanol consumed, respectively."
"The purity of the SA isolated from the culture liquid filtrate reached 100%. The yield of SA was as high as 82% of its amount in the culture liquid filtrate," wrote S.V. Kamzolova and colleagues, G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms.
The researchers concluded: "The quality of the SA produced by the invented method meets the biochemical grade definitions, as is evident from the respiratory and other relevant parameters of rat liver mitochondria upon the oxidation of this SA."
Kamzolova and colleagues published the results of their research in Applied Microbiology and Biotechnology (Chemically assisted microbial production of succinic acid by the yeast Yarrowia lipolytica grown on ethanol. Applied Microbiology and Biotechnology, 2009;83(6):1027-34).
The publisher of the journal Applied Microbiology and Biotechnology can be contacted at: Springer, 233 Spring Street, New York, NY 10013, USA.
This article was prepared by Biotech Week editors from staff and other reports. Copyright 2009, Biotech Week via NewsRx.com.